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for me your second point ‘small range of scanners’ kills much of my interest toward working with ISIS. Then your first point kills the rest of my interest, but this isn’t criticism – just my point of view.
But more to the point of your post it has seemed to me (from afar with little to no knowledge of ISIS) that the comparison is similar to Mac vs PC.
One has historically been more expensive with fewer choices in hardware and a reputation (in some circles) as being more stable or easier to use. Doesn’t make one better than the other, just suited to different parts of the market.